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研究人才詳細資料

出版年月	著作類別	著作名稱	作者	收錄出處
2023-06	期刊論文	Ectopic ATP synthase stimulates the secretion of extracellular vesicles in cancer cells	Kao, Y., Chang, Y., Lai, C.P., Chang, N., Huang, C., Chen, C., Huang, H., Juan, H.	Communications Biology
2023-05	期刊論文	Identification of the High Mannose N‑Glycan Isomers Undescribed by Conventional Multicellular Eukaryotic Biosynthetic Pathways	Liew, C.Y., Luo, H., Yang, T., Hung, A., Magoling, B., Lai, C.P., Ni, C.	Analytical Chemistry
2023-01	期刊論文	Membrane protein modification modulates big and small extracellular vesicle biodistribution and tumorigenic potential in breast cancers in vivo	Magoling, B., Chen,Y., Wu, A.Y., Wong, W.W., Chou, S.T., Huang, H., Sung, Y., Hsieh, H., Huang, P., Lee, K., Huang, K., Chen,R., Chen,Y., Lai, C.P.	Advanced Materials
2022-10	期刊論文	Pharmacokinetics and biodistribution of extracellular vesicles administered intravenously and intranasally to Macaca nemestrina	Driedonks, T., Jiang, L., Carlson, B., Han, Z., Liu, G., Queen, S.E., Shirk, E.N., Gololobova, O., Liao, Z., Nyberg, L.H., Lima, G., Paniushkina L., Garcia-Contreras, M., Schonvisky, K., Castell N., Stover, M., Guerrero-Martin, S., Richardson, R., Smith, B., Machairaki, V., Lai, C.P., Izzi J.M., Hutchinson, E.K., Pate, K.A.M., Witwer, K.W.	Journal of Extracellular Biology
2022-05	期刊論文	Isolation and digital counting of extracellular vesicles from blood via membrane-integrated microfluidics.	Chen, Y., Chen, C., Lai, C.P., Lee, G.	Sensors and Actuators, B: Chemical
2021-08	期刊論文	The power of imaging to understand extracellular vesicles in vivo	Verweij., F., Balaj, L., Boulanger, C., Carter, D., Compeer, E., D’Angelo, G., El Andaloussi, S, Goetz, J.G., Gross, J., Hyenne, V., Krämer-Albers, E., Lai, C.P., Loyer, X., Mark, A., Momma, S., Hoen, E., N., Pegtel, M., Peinado, H., Raposo, G., Rilla, K., Tahara, H., Théry, C., van Royen, M., Vandenbroucke, R., Wehman, A., Witer, K., Wu, Z., Wubbolts, R., Niel, G.V.	Nature Methods
2021-06	期刊論文	Multiplexed bioluminescence-mediated tracking of DNA double-strand break repairs in vitro and in vivo	Chien, J.C., Badr, C.E., Lai, C.P.	Nature Protocols
2021-05	期刊論文	Critical considerations for the development of potency tests for therapeutic applications of mesenchymal stromal cell-derived small extracellular vesicles	Gimona, M., Brizzi, M.F., Choo, A.B.H., Dominici, M., Davidson, S.M., Grillari, J., Hermann, D.M., Hill, A.F., Kleijn, D., Lai, R.C., Lai, C.P., Lim, R., Monguió-Tortajada, M., Muraca, M., Ochiya, T., Ortiz, L.A., Toh, W.S., Yi, Y.W., Witwer, K.W., Giebel, B., Lim, S.K.	Cytotherapy
2021-04	期刊論文	Isolation and recovery of extracellular vesicles using optically-induced dielectrophoresis on an integrated microfluidic platform	Chen, Y., Lai, C.P., Chen, C., Lee, G.	Lab on a Chip
2020-10	期刊論文	Multiresolution Imaging Using Bioluminescence Resonance Energy Transfer Identifies Distinct Biodistribution Profiles of Extracellular Vesicles and Exomeres with Redirected Tropism	Wu, A.Y., Sung, Y., Chen, Y., Chou, S.T., Guo, V., Chien, J.C., Ko, J.J., Yang, A.L., Huang, H., Chuang, J., Wu, S., Ho, M., Ericsson, M., Lin, W., Cheung, C.H.Y., Juan, H., Ueda, K., Chen, Y., Lai, C.P.	Advanced Science
2020-09	期刊論文	A multiplexed bioluminescent reporter for sensitive and non-invasive tracking of DNA double strand break repair dynamics in vitro and in vivo	Chien J.C., Tabet E., Pinkham, K., da Hora, C.C., Chang, J.C., Lin, S., Badr C.E., Lai, C.P.	Nucleic Acids Research
2020-04	期刊論文	Glioblastoma hijacks microglial gene expression to support tumor growth	Maas, S.L.N., Abels, E.R., Van De Haar, L.L., Zhang, X., Morsett L., Sil, S., Guedes, J., Sen, P., Prabhakar, S., Hickman, S.E., Lai, C.P., Ting, D.T., Breakefield, X.O., Broekman, M.L.D., El Khoury, J.	Journal of Neuroinflammation
2020-02	期刊論文	Sonogenetic Modulation of Cellular Activities Using an Engineered Auditory-Sensing Protein	Huang, Y., Fan, C., Hsu, N., Chiu, N., Wu, C., Chang, C., Wu, B., Hong, S., Chang, Y., Wu, A.Y., Guo, V., C, Y., Hsu, W., C, L., Lai, C.P., Yeh, C., Lin, Y.	Nano Letters
2019-12	期刊論文	Delivery of nitric oxide with a nanocarrier promotes tumor vessel normalization and potentiates anti-cancer therapies	Sung, Y., Jin, P., Chu, L., Hsu, F., Wang, M., Chang, C., Chiou, S., Qiu, J.T., Gao, D., Lin, C., Chen, Y., Hsu, Y., Wang, J., Wang, F., Yu, P., Chiang, A., Wu, A.Y., Ko, J.J., Lai, C.P., Lu, T., Chen, Y.	Nature Nanotechnology
2019-04	期刊論文	Methods for systematic identification of membrane proteins for specific capture of cancer-derived extracellular vesicles	Zaborowski, M.P., Lee, K., Na, Y.J., Sammarco, A., Zhang, X., Iwanicki, M., Cheah, P.S., Lin, H.Y., Zinter, M., Chou, C., Fulci, G., Tannous, B.A., Lai, C.P., Birrer, M.J., Weissleder, R., Lee, H., Breakefield, X.O.	Cell Reports
2019-01	期刊論文	Proteomic analysis of extracellular vesicles for cancer diagnostics	Wu, Y.T, Ueda, K., Lai, C.P.	Proteomics
2018-12	期刊論文	Imaging extracellular vesicles: current and emerging methods	Chuo S.T., Chien, J.C., Lai, C.P.	Journal of Biomedical Science
2018-01	期刊論文	Combined delivery of sorafenib and a MEK inhibitor using CXCR4-targeted nanoparticles reduces hepatic fibrosis and prevents tumor development	Sung, Y., Liu, Y., Chao, P., Chang, C., Jin, P., Lin, T., Lin, J., Cheng, H., Wang, J., Lai, C.P., Chen, L., Wu, A.Y., Ho, T., Chiang, T., Gao, D., Duda, D.G., Chen, Y.	Theranostics
2018-01	期刊論文	Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles	Reátegui, E., van der Vos, K.E., Lai, C.P.*, Zeinali, M., Atai, N.A., Aldikacti, B., FloydJr, F.P., Khankhel, A.H., Thapar, V., Hochberg, F.H., Sequist, L.V., Nahed, B.V., Carter, B.S., Toner, M., Balaj, L., Ting, D.T., Breakefield, X.O., Stott, S.L.	Nature Communications
2017-08	期刊論文	Concise Review: Developing Best-Practice Models for the Therapeutic Use of Extracellular Vesicles	Reiner, A.T., Witwer, K.W., van Balkom, B.W.M., de Beer, J., Brodie, C., Corteling, R.L., Gabrielsson, S., Gimona, M., Ibrahim, A.G., de Kleijn, D., Lai, C.P., Lötvall, J., Del Portillo, H.A., Reischl, I.G., Riazifar, M., Salomon, C., Tahara, H., Toh, W.S., Wauben, M.H.M., Yang, V.K., Yang, Y., Yeo, R.W.Y., Yin, H., Giebel, B., Rohde, E., Lim, S.K.	Stem Cells Translational Medicine
2017-03	期刊論文	Obstacles and opportunities in the functional analysis of extracellular vesicle RNA – an ISEV position paper	Mateescu, B., Kowal, E.J., van Balkom, B.W., Bartel, S, Bhattacharyya S.N., Buzás, E.I., Buck, A.H., de Candia, P., Chow, F.W., Das, S., Driedonks, T.A., Fernández-Messina, L., Haderk, F., Hill, A.F., Jones, J.C., Van Keuren-Jensen, K.R., Lai, C.P., Lässer, C., Liegro, I.D., Lunavat, T.R., Lorenowicz, M.J., Maas, S.L., Mäger, I., Mittelbrunn, M., Momma S., Mukherjee, K., Nawaz, M., Pegtel, D.M., Pfaffl, M.W., Schiffelers, R.M., Tahara, H., Théry, C., Tosar, J.P., Wauben, M.H., Witwer, K.W., Nolte-'t Hoen, E.N.	Journal of Extracellular Vesicles
2017-01	專書論文	Tracking Extracellular Vesicles Delivery and RNA Translation Using Multiplexed Reporters	Wu, A.Y., Lai, C.P.	Methods in Molecular Biology
2016-04	期刊論文	Delivery of Therapeutic Proteins via Extracellular Vesicles: Review and Potential Treatments for Parkinson’s Disease, Glioma, and Schwannoma	Justin Hall, Shilpa Prabhakar, Leonora Balaj, Charles P. Lai, Richard A. Cerione, Xandra O. Breakefield	Cellular and Molecular Neurobiology
2016-04	期刊論文	SCS macrophages suppress melanoma by restricting tumor-derived vesicle-B cell interactions	Ferdinando Pucci, Christopher Garris, Charles P. Lai, Andita Newton, Christina Pfirschke, Camilla Engblom, David Alvarez, Melissa Sprachman, Charles Evavold, Angela Magnuson, Ulrich H. von Andrian, Katharina Glatz, Xandra O. Breakefield, Thorsten R. Mempel, Ralph Weissleder, Mikael J. Pittet	Science
2016-01	期刊論文	Directly visualized glioblastoma-derived extracellular vesicles transfer RNA to microglia/macrophages in the brain	Kristan E. van der Vos, Erik R. Abels, Xuan Zhang, Charles P. Lai, Esteban Carrizosa, Derek Oakley, Shilpa Prabhakar, Osama Mardini, Matheus H. W. Crommentuijn, Johan Skog, Anna M. Krichevsky, Anat Stemmer-Rachamimov, Thorsten R. Mempel, Joseph El Khoury, Suzanne E. Hickman, and Xandra O. Breakefield	Neuro-oncology
2015-08	期刊論文	Extracellular Vesicles: Composition, Biological Relevance, and Methods of Study	MikoŁaj P. Zaborowski, Leonora Balaj, Xandra O. Breakefield, and Charles P. Lai	BioScience
2015-05	期刊論文	Survival Benefit and Phenotypic Improvement by Hamartin Gene Therapy in a Tuberous Sclerosis Mouse Brain Model	Shilpa Prabhakar, Xuan Zhang, June Goto, Sangyeul Han, Charles P. Lai, Roderick Bronson, Miguel Sena-Esteves, Vijaya Ramesh, Anat Stemmer-Rachamimov, David J Kwiatkowski, and Xandra O Breakefield	Neurobiology of Disease
2015-05	期刊論文	Visualization and Tracking of Tumour Extracellular Vesicle Delivery and RNA Translation Using Multiplexed Reporters	Charles P. Lai, Edward Y Kim, Christian E Badr, Ralph Weissleder, Thorsten R Mempel, Bakhos A Tannous, and Xandra O Breakefield	Nature Communications
2014-01	期刊論文	Dynamic Biodistribution of Extracellular Vesicles In Vivo Using a Multimodal Imaging Reporter	Charles P. Lai, Osama Mardini, Maria Ericsson, Shilpa Prabhakar, Casey Maguire, John W. Chen, Bakhos A. Tannous, and Xandra O. Breakefield	ACS Nano
2013-10	專書論文	Noninvasive In Vivo Monitoring of Extracellular Vesicles	Charles P. Lai, Bakhos A. Tannous, Xandra O. Breakefield	Bioluminescent Imaging
2013-01	期刊論文	Selective Inhibition of Cx43 Hemichannels by Gap19 and Its Impact on Myocardial Ischemia/Reperfusion Injury	Nan Wang, Elke De Vuyst, Raf Ponsaerts, Kerstin Boengler, Nicolás Palacios-Prado, Joris Wauman, Charles P. Lai, Marijke De Bock, Elke Decrock, Mélissa Bol, Mathieu Vinken, Vera Rogiers, Jan Tavernier, W Howard Evans, Christian C Naus, Feliksas F Bukauskas, Karin R Sipido, Gerd Heusch, Rainer Schulz, Geert Bultynck, and Luc Leybaert	Basic Research in Cardiology
2012-06	期刊論文	Role of Exosomes/Microvesicles in the Nervous System and Use in Emerging Therapies	Charles P. Lai, Xandra O. Breakefield	Frontiers in Physiology
2012-01	期刊論文	Pannexin1 Drives Multicellular Aggregate Compaction via a Signaling Cascade That Remodels the Actin Cytoskeleton	Brian A. Bao, Charles P. Lai, Christian C. Naus, Jeffrey R. Morgan	Journal of Biological Chemistry
2009-09	期刊論文	Ca2+ Regulation of Connexin 43 Hemichannels in C6 Glioma and Glial Cells	Elke De Vuyst, Nan Wang, Elke Decrock, Marijke De Bock, Mathieu Vinken, Marijke Van Moorhem, Charles P. Lai, Maxime Culot, Vera Rogiers, Romeo Cecchelli, Christian C. Naus, W Howard Evans, Luc Leybaert	Cell Calcium
2009-09	期刊論文	Pannexin2 as a Novel Growth Regulator in C6 Glioma Cells	Charles P. Lai, John F. Bechberger, Christian C. Naus	Oncogene
2009-01	專書論文	Connexin and Pannexins: Two Gap Junction Families Mediating Glioma Growth Control	Charles P. Lai, Christian C. Naus	Astrocytes in (Patho)Physiology of the Nervous System
2009-01	專書論文	Pannexins	Charles P. Lai, Christian C. Naus, John F. Bechberger	Encyclopedia of Cancer, 2nd Edition
2008-09	期刊論文	Connexin43 Hemichannel Contributes to the Propagation of Apoptotic Cell Death in a Rat C6 Glioma Cell Model	Elke Decrock, Elke De Vuyst, Mathieu Vinken, Marijke Van Moorhem, K Vranckx, Nan Wang, L Van Laeken, Marijke De Bock, K D'Herde, Charles P. Lai, Vera Rogiers, W. Howard Evans, Christian C. Naus, Luc Leybaert	Cell Death and Differentiation
2007-02	期刊論文	Tumor-Suppressive Effects of Pannexin 1 in C6 Glioma Cells	Charles P. Lai, John F. Bechberger, Roger J. Thompson, Brian A. MacVicar, Roberto Bruzzone, Christian C. Naus	Cancer Research
2006-08	期刊論文	Passing Potassium With and Without Gap Junctions	Michael G. Kozoriz, Dave C. Bates, Stephen R. Bond, Charles P. Lai, and David M. Moniz	Journal of Neuroscience