Peroxiredoxin 3 regulates breast cancer progression via ERK-mediated MMP-1 expression
Chua PJ, Ow SH, Ng CT, Huang WH, Low JT, Tan PH, Chan MWY* and Bay BH*
Cancer Cell International
2024-01
期刊論文
Ultrasensitive upconversion nanoparticle immunoassay for human serum cardiac troponin I detection achieved with resonant waveguide grating
Tseng YT, Chiu YC, Pham VD, Wu WH, Le-Vu TT, Wang CH, Kuo SW, Chan MWY, Lin CH, Li SC, Li YD, Kan HC, Lin JY, Chau LK, Hsu CC*
ACS Sensors
2023-11
期刊論文
H. pylori-induced NF-κB-PIEZO1-YAP1-CTGF axis drives gastric cancer progression and cancer-associated fibroblast-mediated tumour microenvironment remodeling
Chen B, Liu X, Yu P, Xie F, Kwan JSH, Chan WN, Fang C, Zhang J, Cheung AHK, Chow C, Leung GWM, Leung KT, Shi S, Zhang B, Wang S, Xu D, Fu K, Wong CC, Wu WKK, Chan MWY, Tang PMK, Tsang CM, Lo KW, Tse GMK, Yu J, To KF
Clinical and Translational Medicine
2023-09
期刊論文
Targeting PPAR-gamma counteracts tumor adaptation to immune-checkpoint blockade in hepatocellular carcinoma
Xiong Z, Chan SL, Zhou J, Vong JSL, Kwong TT, Zeng X, Wu H, Cao J, Tu Y, Feng Y, Yang W, Wong PPC, Si-Tou WWY, Liu X, Wang J, Tang W, Liang Z, Lu J, Li KM, Low JT, Chan MWY, Leung HHW, Chan AWH, To KF, Yip KYL, Lo YMD, Sung JJY, Cheng ASL
Gut
2023-09
期刊論文
phthalate exposure elicits offspring IFN-λ upregulation: Insights from birth cohort, murine model, and in vitro mechanistic analysis
Kuo FC, Tsai ML, Wu ST, Li SS, Wu CF, Wang SL, Chan MWY, Suen JL, Wu MT, Hung CH
Food and Chemical Toxicology
2023-05
期刊論文
Prenatal DEHP exposure predicts neurological disorders via transgenerational epigenetics
Tran MT, Kuo FC, Low JT, Chuang YM, Sultana S, Huang WL, Lin ZY, Lin GL, Wu CF, Li SS, Suen JL, Hung CH, Wu MT and Chan MWY*
Scientific Reports
2023-03
期刊論文
Association of SNPs in the PAI1 Gene with Disease Recurrence and Clinical Outcome in Bladder Cancer
Murakami K, Furuya H, Hokutan K, Goodison S, Pagano I, Chen R, Shen CH, Chan MWY, Ng AC, Kobayashi T, Ogawa O, Miyake M, Thornquist M, Shimizu Y, Hayashi K, Kagan J, Srivastava S, Wang Z, Yu H and Rosser CJ
International Journal of Molecular Sciences
2023-02
期刊論文
Editorial: HF2Cancer: Exploring bidirectional interaction between cardiovascular diseases and cancer
Nebigil C and Chan MW
Frontiers in Cardiovascular Medicine
2022-10
期刊論文
Quantitative and amplification-free detection of SOCS-1 CpG methylation percentage analyses in gastric cancer by fiber optic nanoplasmonic biosensor
Guthula LS, Yeh KT, Huang WL, Chen CH, Chen YL, Huang CJ, Lai-Kwan Chau, Chan MWY, Lin SH
Biosensors & Bioelectronics
2022-09
期刊論文
MCM6 is a critical transcriptional target of YAP to promote gastric tumorigenesis and serves as a therapeutic target
Wang Y, Chen H, Liu W, Zhang Y, Cheung AHK, Zhang J, Liang L, Zhou Z, Wong CC, Wu WKK, Chan MW, Cheng ASL, Ma BBY, Yu J, Lo KW, To KF, and Kang W
Theranostics
2022-08
期刊論文
Association of Chinese herbal medicine use with the depression risk among the long-term breast cancer survivors: A longitudinal follow-up study
Yang SY, Livneh H, Jhang JS, Yen SW, Huang HL, Chan MWY, Lu MC, Yeh CC, Wei CK, Tsai TY
Frontiers in Psychology
2022-02
期刊論文
Interplay between ceRNA and Epigenetic Control of microRNA: Modelling Approaches with Application to the Role of Estrogen in Ovarian Cancer
Huang TW, Cheng FH, Yan CC, Chuang YM, Cho CH, Lai HC, Shieh SF, Chan MW*, Tsai JC*
International Journal of Molecular Sciences
2022-02
期刊論文
PCDHB15 as a potential tumor suppressor and epigenetic biomarker for breast cancer
Chiang CC, Lin GL, Yang SY, Tu CW, Huang WL, Wei CF, Wang FC, Lin PJ, Huang WH, Chuang YM, Lee YT, Yeh CC, Chan MW* and Hsu YC*
Oncology Letters
2021-11
期刊論文
Reinforcement of Environmental DNA Based Methods (Sensu Stricto) in Biodiversity Monitoring and Conservation: A Review
Banerjee P, Dey G, Antognazza CM, Sharma RK, Maity JP, Chan MW, Huang YH, Lin PY, Chao HC, Lu CM, Chen CY
Biology (Basel)
2021-09
期刊論文
Depth-resolved microbial diversity and functional profiles of trichloroethylene-contaminated soils for Biolog EcoPlate-based biostimulation strategy.
Deciphering Bacterial Community Structure, Functional Prediction and Food Safety Assessment in Fermented Fruits Using Next-Generation 16S rRNA Amplicon Sequencing
IRAK2, an IL1R/TLR Immune Mediator, Enhances Radiosensitivity via Modulating Caspase 8/3-Mediated Apoptosis in Oral Squamous Cell Carcinoma
Yu CC, Chan MW, Lin HY, Chiou WY, Lin RI, Chen CA, Lee MS, Chi CL, Chen LC, Huang LW, Chew CH, Hsu FC, Yang HJ, Hung SK.
Frontiers in Oncology
2021-05
期刊論文
CCRK – a hub for liver metastasis and cancer (Commentary)
Low JT, Lin GL, and Chan MW*
Cellular & Molecular Immunology
2021-05
期刊論文
Firing up Cold Tumors-Targeting the Epigenetic Machinery to Enhance Cancer Immunotherapy (Editorial)
Lin GL, Tsai LH, Kuppen PJK*, Chan MW*
Epigenomes
2021-04
期刊論文
Cyproheptadine, an epigenetic modifier, exhibits anti-tumor activity by reversing the epigenetic silencing of IRF6 in urothelial carcinoma
Jou YC, Lin GL, Lin HY, Huang WH, Chuang YM, Lin RI, Chen PC, Wu SF, Shen CH*, Chan MW*
Cancer Cell International
2021-04
期刊論文
Methylomic analysis identifies C11orf87 as a novel epigenetic biomarker for GI cancers
Tran M, Yeh KT, Chuang YM, Hsu PY, Low JT, Kumari H, Lee YT, Chen YC, Huang WH, Jin H, Lin SH*, Chan MW*.
PLOS ONE
2021-03
期刊論文
NOTCH3, a crucial target of miR-491-5p/miR-875-5p, promotes gastric carcinogenesis by upregulating PHLDB2 expression and activating Akt pathway
Kang W, Zhang J, Huang T, Zhou Y, Wong CC, Chan RCK, Dong Y, Wu F, Zhang B, Wu WKK, Chan MWY, Cheng ASL, Yu J, Wong N, Lo KW, To KF
Oncogene
2021-02
期刊論文
Epigenetic Silencing of STAT3-Targeted miR-193a, by Constitutive Activation of JAK/STAT Signaling, Leads to Tumor Progression Through Overexpression of YWHAZ in Gastric Cancer
Wei KL, Chou JL, Chen YC, Low JT, Lin GL, Liu JL, Chang TS, Chen WM, Hsieh YY, Yan PS, Chuang YM, Lin JMJ, Wu SF, Chiang MK, Li C, Wu CS, Chan MW
Frontiers in Oncology
2021-01
期刊論文
Gold nanorods conjugated upconversion nanoparticles nanocomposites for simultaneous bioimaging, local temperature sensing and photothermal therapy of OML-1 oral cancer cells
Vu DT, Vu-Le TT, Nguyen VN, Le QM, Wang CR, Chau LK, Yang TS, Chan MW, Lee CI, Ting CC, Lin JY, Kan HC, and Hsu CC
International Journal of Smart and Nano Material
2020-12
期刊論文
Combinatorial epigenetic and immunotherapy in breast cancer management: A literature review
Lee YT, Chuang YM, and Chan MW*
Epigenomes
2020-12
期刊論文
Environmental factor-mediated transgenerational inheritance of Igf2r hypomethylation and pulmonary allergic response via targeting dendritic cells
Suen JL, Wu TT, Li YH, Lee CL, Kuo FC, Yan P, Wu CF, Tran M, Wang CJ, Hung CH, Wu MT*, Chan MW* and Huang SK*.
Froniters in Immunology
2020-10
期刊論文
FGF18-FGFR2 signaling triggers the activation of c-Jun-YAP1 axis to promote carcinogenesis in a subgroup of gastric cancer patients and indicates translational potential.
Zhang J, Wong CC, Leung KT, Wu F, Zhou Y, Tong JHM, Chan RCK, Li H, Wang Y, Yan H, Liu L, Wu WKK, Chan MWY, Cheng ASL, Yu J, Wong N, Lo KW, To KF, Kang W
Oncogene
2020-08
期刊論文
2,4-Diamino-Quinazoline, a Wnt Signaling Inhibitor, Suppresses Gastric Cancer Progression and Metastasis.
Bacteria pathogens drive host colonic epithelial cell promoter hypermethylation of tumor suppressor genes in colorectal cancer
Xia X, Wu WKK, Wong SH, Liu D, Kwong TNY, Nakatsu G, Yan PS, Chuang YM, Chan MW, Coker OO, Chen Z, Yeoh YK, Zhao L, Wang X, Cheng WY, Chan MTV, Chan PKS, Sung JJY, Wang MH, Yu J
Microbiome
2020-06
期刊論文
Differential DNA methylation profiles of peripheral blood mononuclear cells in allergic asthmatic children following dust mite immunotherapy
Wang CM, Chang CB, Lee SP, W-Y Chan M, Wu SF
Journal of microbiology, immunology, and infection
2020-05
期刊論文
Review on the Role of Epigenetic Modifications in Doxorubicin-Induced Cardiotoxicity
Kumari H, Huang WH, Chan MW
Frontiers in cardiovascular medicine
2020-03
期刊論文
Decreased risk of colorectal cancer among patients with type 2 diabetes receiving Chinese herbal medicine: a population-based cohort study
Jhang JS, Livneh H, Yang SY, Huang HJ, Chan MWY, Lu MC, Yeh CC, Tsai TY.
BMJ open diabetes research & care
2020-02
期刊論文
Emerging Challenges of Radiation-Associated Cardiovascular Dysfunction (RACVD) in Modern Radiation Oncology: Clinical Practice, Bench Investigation, and Multidisciplinary Care
Lee MS, Liu DW, Hung SK, Yu CC, Chi CL, Chiou WY, Chen LC, Lin RI, Huang LW, Chew CH, Hsu FC, Chan MWY*, Lin HY*
Frontiers in Cardiovascular Medicine
2019-11
期刊論文
Dendritic cell upregulation of programmed death ligand-1 via DNA demethylation inhibits experimental autoimmune encephalomyelitis
Chang CB, Lee SP, Chen WM, Wang CM, Song YC, Chan MW, Wu SF
Journal of Autoimmunity
2019-09
期刊論文
Prokineticin Receptor-1 Signaling Inhibits Dose- and Time-Dependent Anthracycline-Induced Cardiovascular Toxicity Via Myocardial and Vascular Protection
Gasser A, Chen YW, Audebrand A, Daglayan A, Charavin M, Escoubet B, Karpov P, Tetko I, Chan MW, Cardinale D, Désaubry L and Nebigil CG
JACC: CardioOncology
2019-09
期刊論文
c-Myc Acts as a Competing Endogenous RNA to Sponge miR-34a, in the Upregulation of CD44, in Urothelial Carcinoma
Chen PC, Yu CC, Huang WY, Huang WH, Chuang YM, Lin RI, Lin JM, Lin HY, Jou YC, Shen CH, Chan MW*
Cancers
2019-06
期刊論文
Methylomics analysis identifies a putative STAT3 target, SPG20, as a noninvasive epigenetic biomarker for early detection of gastric cancer
3. Wei KL, Chou JL, Chen YC, Jin H, Chuang YM, Wu CS* and Chan MW*
PLOS ONE
2019-06
期刊論文
Paired Box-1 (PAX1) Activates Multiple Phosphatases and Inhibits Kinase Cascades in Cervical Cancer
Su PH, Lai HC, Huang RL, Chen LY, Wang YC, Wu TI, Chan MW, Liao CC, Chen CW, Lin WY, Chang CC
Scientific Reports
2019-03
期刊論文
E2F6 Functions as a Competing Endogenous RNA, and Transcriptional Repressor, to Promote Ovarian Cancer Stemness
Cheng FH, Lin HY, Hwang TW, Chen YC, Huang RL, Chang CB, Yang W, Lin RI, Lin CW, Chen GC, Mai SY, Lin JM, Chuang YM, Chou JL, Kuo LW, Li C, Cheng AS, Lai HC, Wu SF, Tsai JC*, and Chan MW*
Cancer Science
2019-03
期刊論文
TET1 reprograms the epithelial ovarian cancer epigenome and reveals casein kinase 2α as a therapeutic target
Chen LY, Huang RL, Chan MWY, Yan PS, Huang TS, Wu RC, Suryo Rahmanto Y, Su PH, Weng YC, Chou JL, Chao TK, Wang YC, Shih IM, Lai HC
Journal of Pathology
2019-03
期刊論文
ZNF671 DNA methylation as a molecular predictor for the early recurrence of serous ovarian cancer
Mase S, Shinjo K, Totani H, Katsushima K, Arakawa A, Takahashi S, Lai HC, Lin RI, Chan MW, Sugiura-Ogasawara M, Kondo Y
Cancer Science
2019-01
期刊論文
Aberrant Enhancer Hypomethylation Drives Hepatic Carcinogenesis through Global Transcriptional Reprogramming
Xiong L, Wu F, Wu Q, Xu L, Cheung OK, Kang W, Mok MT, Szeto LL, Lun CY, Lung RW, Zhang J, Yu KH, Lee SD, Huang G, Qang CM, Liu J, Yu Z, Yu DY, Chou JL, Huang WH, Feng B, Cheung YS, Lai PB, Tan P, Wong N, Chan MW, Huang TH, Yip KY, Cheng AS, To KF
Nature Communications
2018-12
期刊論文
GATA3 as a master regulator and therapeutic target in ovarian high-grade serous carcinoma stem cells
Chen HJ, Huang RL, Liew PL, Su PH, Chen LY, Weng YC, Chang CC, Wang YC, Chan MW, Lai HC
International Journal of Cancer
2018-11
期刊論文
Dust mite allergen-specific immunotherapy increases IL4 DNA methylation and induces Der p-specific T cell tolerance in children with allergic asthma
Wang CM, Chang CB, Chan MW, Wen ZH, Wu SF*
Cellular & Molecular Immunology
2018-02
期刊論文
Epigenetic Biomarkers in Cancer
Cheng YY, Jin HC, Chan MWY, Chu WK, Grusch M
Disease Markers
2018-02
期刊論文
Epigenetic silencing of the dual-role signal mediator, ANGPTL4 in tumor tissues and its overexpression in the urothelial carcinoma microenvironment
Hsieh HY, Jou YC, Tung CL, Tsai YS, Wang YH, Chi CL, Lin RI, Hung SK, Chuang YM, Wu SF, Li C, Shen CH, Chan MWY*, Hsu CD*
Oncogene
2017-09
期刊論文
DNA Methylation as a Noninvasive Epigenetic Biomarker for the Detection of Cancer
Leygo C, Williams M, Jin HC, Chan MWY, Chu WK, Grusch M, Cheng YY*
Disease Markers
2017-09
期刊論文
Irradiation enhanced risks of hospitalised pneumonopathy in lung cancer patients: a population-based surgical cohort study
Hung SK, Chen YC, Chiou WY, Lai CL, Lee MS, Lo YC, Chen LC, Huang LW, Chien NC, Li SC, Liu DW, Hsu FC, Tsai SJ, Chan MW, Lin HY
BMJ Open
2017-08
期刊論文
Hard clam extracts induce atypical apoptosis in human gastric cancer cells.
Song EJ, Chan MWY, Shin JW, Chen CC
Experimental and Therapeutic Medicine
2016-09
期刊論文
Aberrant JAK/STAT Signaling Suppresses TFF1 and TFF2 through Epigenetic Silencing of GATA6 in Gastric Cancer
Wu CS, Wei KL, Chou JL, Lu CK, Hsieh CC, Lin JM, Deng YF, Hsu WT, Wang HM, Leung CH, Ma DL, Li C, Chan MW
International Journal of Molecular Sciences
2016-07
期刊論文
Epigenetic silencing of the NR4A3 tumor suppressor, by aberrant JAK/STAT signaling, predicts prognosis in gastric cancer
Yeh CM, Chang LY, Lin SH, Chou JL, Hsieh, HY, Zeng LH, Chuang SY, Wang HW, Dittner C, Lin CY, Lin JM, Huang YT, Ng EK, Chang AS, Wu SF, Lin J, Yeh KT* and Chan MW*
Scientific Reports
2016-06
期刊論文
Dysregulated Lysine Acetyltransferase 2B Promotes Inflammatory Bowel Disease Pathogenesis Through Transcriptional Repression of Interleukin-10
Bai AH, Wu WK, Xu L, Wong SH, Go MY, Chan AW, Harbord M, Zhang S, Chen M, Wu JC, Chan MW, Chan MT, Chan FK, Sung JJ, Yu J, Cheng AS, Ng SC
Journal of Crohn's and Colitis
2016-05
期刊論文
Hemolytic E. coli Promotes Colonic Tumorigenesis in Females
Jin Y, Tang S, Li W, Ng SC, Chan MW, Sung JJ, Yu J.
Cancer Research
2016-04
期刊論文
Epigenetic silencing of GDF1 disrupts SMAD signaling to reinforce gastric cancer development
Yang W, Mok MT, Li MS, Kang W, Wang H, Chan AW, Chou JL, Chen J, Ng EK, To KF, Yu J, Chan MW, Chan FK, Sung JJ, Cheng AS*
Oncogene
2016-01
期刊論文
Cyproheptadine exhibits antitumor activity in urothelial carcinoma cells by targeting GSK3β to suppress mTOR and β-catenin signaling pathways
Hsieh HY, Shen CH, Lin RI, Feng YM, Huang SY, Wang YH, Wu SF, Hsu CD*, Chan MW*
Cancer Letters
2016-01
期刊論文
Guizhi Fuling Wan as a novel agent for intravesical treatment for bladder cancer in mouse model
Oncogene-tumor suppressor gene feedback interactions and their control
Aguda BD*, del Rosario RC, Chan MW
Mathematical Biosciences and Engineering
2015-10
期刊論文
Methylomics analysis identifies ZNF671 as an epigenetically repressed novel tumor suppressor and a potential non-invasive biomarker for the detection of urothelial carcinoma
Yeh CM, Chen PC, Hsieh HY, Jou YC, Lin CT, Tsai MH, Huang WY, Wang YT, Lin RI, Chen SS, Tung CL, Wu SF, Chang DC, Shen CH, Hsu CD, Chan MW*
Oncotarget
2015-09
期刊論文
Global profiling of histone modifications in the polyomavirus BK virion minichromosome
Fang CY, Shen CH, Wang M, Chen PL, Chan MW, Hsu PH, Chang D*
Virology
2015-03
期刊論文
DNA methylation profiles and biomarkers of oral squamous cell carcinoma
Li YF, Hsiao YH, Lai YH, Chen YC, Chen YJ, Chou JL, Chan MW, Lin YH, Tsou YA, Tsai MH, Tai CK
Epigenetics
2015-01
期刊論文
DNA methylome analysis identifies epigenetic silencing of FHIT as a determining factor for radiosensitivity in oral cancer: an outcome-predicting and treatment-implicating study
Lin HY, Hung SK, Lee MS, Chiou WY, Huang TT, Tseng CE, Shih LY, Lin RI, Lin JM, Lai YH, Chang CB, Hsu FC, Chen LC, Tsai SJ, Su YC, Li SC, Lai HC, Hsu WL, Liu DW, Tai CK, Wu SF, Chan MW*
Oncotarget
2015-01
期刊論文
Hypermethylation of the TGF-beta target, ABCA1 is associated with poor prognosis in ovarian cancer patients
Chou JL, Huang RL, Shay J, Chen LY, Lin SJ, Yan PS, Chao WT, Lai YH, Lai YL, Chao TK, Lee CI, Tai CK, Wu SF, Nephew KP, Huang TH, Lai HC*, and Chan MW*
Clinical Epigenetics
2014-12
期刊論文
A mathematical model of bimodal epigenetic control of miR-193a in ovarian cancer stem cells
Cheng FH, Aguda BD, Tsai JC, Kochańczyk M, Lin MJ, Chen GC, Lai HC, Nephew KP, Hwang TW*, Chan MW*
PLOS ONE
2014-11
期刊論文
Epigenetic silencing of ARNTL, a circadian gene and potential tumor suppressor in ovarian cancer
Yeh CM, Shay J, Zeng TC, Chou JL, Huang TH, Lai HC, Chan MW*
International Journal of Oncology
2014-10
期刊論文
FT-IR Microspectrometry Reveals the Variation of Membrane Polarizability due to Epigenomic Effect on Epithelial Ovarian Cancer
Hsu MM, Huang PY, Lee YC, Fang YC, Chan MW, Lee CI
International Journal of Molecular Sciences
2014-09
期刊論文
NKCC1 mediates traumatic brain injury-induced hippocampal neurogenesis through CREB phosphorylation and HIF-1α expression
Lu KT, Huang TC, Wang JY, You YS, Chou JL, Chan MW, Wo PY, Amstislavskaya TG, Tikhonova MA, Yang YL
Pflugers Archiv : European Journal of Physiology
2014-09
期刊論文
Promoter hypermethylation and silencing of tissue factor pathway inhibitor-2 in oral squamous cell carcinoma
Lai YH, He RY, Chou JL, Chan MW, Li YF, Tai CK
Journal of Translational Medicine
2014-08
期刊論文
Long-term low-dose exposure of human urothelial cells to sodium arsenite activates lipocalin-2 via promoter hypomethylation
Wang HH, Wu MM, Chan MW, Pu YS, Chen CJ, Lee TC.
Archives of Toxicology
2014-06
期刊論文
Low-dose 5-aza-2'-deoxycytidine pretreatment inhibits experimental autoimmune encephalomyelitis by induction of regulatory T cells
Chan MW, Chang CB, Tung CH, Sun J, Suen JL, Wu SF
Molecular Medicine
2014-04
期刊論文
Hypomethylation signature of tumor-initiating cells predicts poor prognosis of ovarian cancer patients
Liao YP, Chen LY, Huang RL, Su PH, Chan MW, Chang CC, Yu MH, Wang PH, Yen MS, Nephew KP, Lai HC
Human Molecular Genetics
2014-02
期刊論文
Association between cytokines and methylation of SOCS-1
in serum of patients with ankylosing spondylitis
Lai NS, Chou JL, Chen GC, Liu SQ, Lu MC, Chan MW
Molecular Biology Reports
2013-05
期刊論文
SOCS-1 Promoter Methylation and Treatment Response in Chronic Hepatitis C Patients Receiving Pegylated-Interferon/Ribavirin
Unexpected Close Surgical Margin in Resected Buccal Cancer: Very Close Margin and DAPK Promoter Hypermethylation Predict Poor Clinical Outcomes
Lin HY, Huang TT, Lee MS, Hung SK, Lin RI, Tseng CE, Chang SM, Chiou WY, Hsu, FC, Hsu WL, Liu DW, Su YC, Li SC, Chan MW*
Oral Oncology
2013-02
期刊論文
The investigation of a traditional chinese medicine, Guizhi Fuling Wan (GFW) as an Intravesical therapeutic agent for urothelial carcinoma of the bladder
Lu CC, Lin MY, Chen SY, Shen CH, Chen LG, Hsieh HY, Chan MW*, Hsu CD*
BMC Complementary and Alternative Medicine
2013-01
期刊論文
Epigenetic silencing of PTPRR activates MAPK signaling, promotes metastasis and serves as a biomarker of invasive cervical cancer
Su PH, Lin YW, Huang RL, Liao YP, Lee HY, Wang HC, Chao TK, Chen CK, Chan MW, Chu TY, Yu MH, Lai HC*
Oncogene
2013-01
期刊論文
Helicobacter pylori causes epigenetic dysregulation of FOXD3 to promote gastric carcinogenesis
Cheng AS*, Li MS, Kang W, Cheng VY, Chou JL, Lau SS, Go MY, Lee CC, Ling TK, Ng EK, Yu J, Huang TH, To KF, Chan MW, Sung JJ, Chan FK
Gastroenterology
2012-10
期刊論文
Methods for high-throughput MethylCap-Seq data analysis
Rodriguez BA, Frankhouser D, Murphy M, Trimarchi M, Tam HH, Curfman J, Huang R, Chan MW, Lai HC, Parikh D, Ball B, Schwind S, Blum W, Marcucci G, Yan P*, Bundschuh R*
BMC Genomics
2012-08
期刊論文
Dichotomy effects of AKT signaling in breast cancer
Peng Z, Weber JC, Han Z, Shen R, Zhou W, Scott JR, Chan MW, Lin HJ*
Molecular Cancer
2012-08
期刊論文
Growth Inhibition of ovarian tumor-initiating cells by niclosamide
Yo YT, Lin YW, Wang YC, Balch C, Huang RL, Chan MW, Sytwu HK, Chen CK, Chang CC, Nephew KP, Huang TH, Yu MH, Lai HC*
Molecular Cancer Therapeutics
2011-12
期刊論文
The high incidence of JC virus infection in urothelial carcinoma tissue in Taiwan
Shen CH, Wu JD, Hsu CD, Jou YC, Lin CT, Wang M, Wu SF, Chan MW, Chiang MK, Fang CY, Chang D*
Journal of Medical Virology
2011-10
期刊論文
Analysis of DNA methylation in human BK virus
Chang CF, Wang M, Fang CY, Chen PL, Wu SF, Chan MW*, Chang DC*
Virus Genes
2011-07
期刊論文
ChIP-seq defined genome-wide map of TGFβ/SMAD4 targets: implications with clinical outcome of ovarian cancer patients
Kennedy BA, Deatherage DE, Gu F, Tang B, Chan MW, Nephew KP, Huang TH, Jin VX*
PLoS One
2011-06
期刊論文
Aberrant TGFβ/SMAD4 signaling contributes to epigenetic silencing of a putative tumor suppressor, RunX1T1 in ovarian cancer
Yeh KT, Chen TH, Yang HW, Chou JL, Chen LY, Yeh CM, Chen YH, Lin RI, Su HY, Chen GC, Deatherage DE, Huang YW, Yan PS, Lin HJ, Nephew KP, Huang TH, Lai HC, Chan MW*
Epigenetics
2011-05
期刊論文
Distinct DNA methylation epigenotypes in bladder cancer from different Chinese sub-populations and its implication in cancer detection using voided urine
Chen PC, Tsai MH, Yip SK, Jou YC, Ng CF, Chen Y, Wang X, Huang W, Tung CL, Chen GC, Huang MM, Tong JH, Song EJ, Chang DC, Hsu CD, To KF, Shen CH, Chan MW*
BMC Medical Genomics
2010-11
期刊論文
TGF-beta: friend or foe? The Role of TGF-beta/SMAD signaling in epigenetic silencing of ovarian cancer and its implication in epigenetic therapy
Chou JL, Chen LY, Lai HC, and Chan MW*
Expert Opinion on Therapeutic Targets
2010-08
期刊論文
High Dickkopf-1 expression is associated with poor prognosis in patients with advanced urothelial carcinoma
Shen CH, Hsieh HY, Wang YH, Chen SY, Tung CL, Wu JD, Lin CT, Chan MWY, Hsu CD*, Chang DC*
Experimental and Therapeutic Medicine
2010-06
期刊論文
Putative tumor-suppressor gene DAB2 is frequently down regulated by promoter hypermethylation in nasopharyngeal carcinoma
Tong JH, Ng DC, Chau SL, So KK, Leung PP, Lee TL, Lung RW, Chan MW, Chan AW, Lo KW and To KF*
BMC Cancer
2010-03
期刊論文
Promoter hypermethylation of FBXO32, a novel TGF-beta/SMAD4 target gene and tumor suppressor, is associated with poor prognosis in human ovarian cancer
Chou JL, Su HY, Chen LY, Liao YP, Hartman-Frey C, Lai YH, Yang HW, Deatherage DE, Kuo CT, Huang YW, Yan PS, Hsiao SH, Tai CK, Lin HJ, Davuluri RV, Chao TK, Nephew KP, Huang THM, Lai HC and Chan MW*
Laboratory Investigation
2009-12
期刊論文
Promoter methylation of IGFBP-3 and p53 expression in ovarian endometrioid carcinoma
Torng PL, Lin Cw, Chan MW, Yang HW, Huang SC and Lin CT*
Molecular Cancer
2009-10
期刊論文
Identification of candidate epigenetic biomarkers for ovarian cancer detection
Huang YW, Jansen RA, Fabbri E, Potter D, Liyanarachchi S, Chan MW, Liu JC, Crijns APG, Brown R, Nephew KP, Van Der Zee AGJ, Cohn D, Yan PS, Huang THM, and Lin HJ*
Oncology Reports
2009-07
期刊論文
An integrative ChIP-chip and gene expression profiling to model SMAD regulatory modules
Qin H, Chan MW, Liyanarachchi S, Balch C, Potter D, Souriraj IJ, Cheng ASL, Agosto-Perez FJ, Nikonova EV, Yan PS, Lin HJ, Nephew KP, Saltz JH, Showe LC, Huang TH*, and Davuluri RV*
BMC Systems Biology
2009-04
期刊論文
Progressive increase of genetic alteration in urinary bladder cancer by combined allelotyping analysis and comparative genomic hybridization
Chan MW*, Hu AB, Yip SK, Ng CF, Lo KW, Tong JHM, Chan AWH, Chueng HY, Wong WS, Chan PSF, Lai FMM, and To KF
International Journal of Oncology
2008-11
期刊論文
Fibroblasts isolated from common sites of breast cancer metastasis enhance cancer cell growth rates and invasiveness in an interleukin-6-dependent manner
Studebaker AW, Storci G, Werbeck JL, Sansone P, Sasser AK, Tavolari S, Huang T, Chan MW, Marini FC, Rosol TJ, Bonafe M, and Hall BM*
Cancer Research
2008-09
期刊論文
Aberrant Transforming Growth Factor-beta 1 Signaling and SMAD4 Nuclear Internalization Confer Epigenetic Repression of ADAM19 in Ovarian Cancer
Chan MW, Huang YW, Hartman-Frey C, Kuo CT, Deatherage D, Qin H, Cheng ASL, Yan PS, Davuluri RV, Huang TH, Nephew KP*, and Lin HJ*
Neoplasia
2008-07
期刊論文
Identification of novel DNA methylation markers in cervical cancer
HC Lai*, YW Lin, THM Huang, PS Yan, RL Huang, HC Wang, J Liu, MWY Chan, TY Chu, CA Sun, CC Chang and Yu MH
International Journal of Cancer
2008-06
期刊論文
Identification and Characterization of Ovarian Cancer-Initiating Cells from Primary Human Tumors
Zhang S, Balch C, Chan MW, Lai HC, Matei D, Schilder JM, Yan PS, Huang THM and Nephew KP*
Cancer Research
2008-03
期刊論文
Epithelial progeny of estrogen-exposed breast progenitor cells display a cancer-like methylome
Cheng AS, Culhane AC, Chan MW, Venkataramu CR, Ehrich M, Nasir A, Rodriguez BA, Liu J, Yan PS, Quackenbush J, Nephew KP, Yeatman TJ and Huang TH*
Cancer Research
2007-12
期刊論文
Targeted inhibition of COX-2 expression by RNA interference suppresses tumor growth and potentiates chemosensitivity to cisplatin in human gastric cancer cells
Chan MW, Wong CY, Cheng AS, Chan VY, Chan KK, To KF, Chan FL, Sung JJY and Leung WK*
Oncology Reports
2007-06
期刊論文
FOXP3 is an X-linked breast cancer suppressor gene and an important repressor of the HER-2/ErbB2 oncogene
Zuo T, Wang L, Morrison C, Chang X, Zhang H, Li W, Liu Y, Wang Y, Liu X, Chan MW, Liu JQ, Love R, Liu CG, Godfrey V, Shen R, Huang TH, Yang T, Park BK, Wang CY, Zheng P*, Liu Y*
Cell
2007-05
期刊論文
Detection of hypermethylated DNA or cyclooxygenase-2 messenger RNA in fecal samples of patients with colorectal cancer or polyps.
Leung WK*, To KF, Man EP, Chan MW, Hui AJ, Ng SS, Lau JY, Sung JJ
American Journal of Gastroenterology
2006-02
期刊論文
Combinatorial analysis of transcription factor partners reveals recruitment of c-MYC to estrogen receptor-alpha responsive promoters.
Cheng AS, Jin VX, Fan M, Smith LT, Liyanarachchi S, Yan PS, Leu YW, Chan MW, Plass C, Nephew KP, Davuluri RV, Huang TH*
Molecular Cell
2005-10
期刊論文
Hypermethylation of 18S and 28S ribosomal DNAs predicts progression-free survival in patients with ovarian cancer.
Chan MW, Wei SH, Wen P, Wang Z, Matei DE, Liu JC, Liyanarachchi S, Brown R, Nephew KP, Yan PS, Huang TH*
Clinical Cancer Research
2005-10
期刊論文
Quantitative detection of promoter hypermethylation in multiple genes in the serum of patients with colorectal cancer.
Leung WK*, To KF, Man EP, Chan MW, Bai AH, Hui AJ, Chan FK, Sung JJ
American Journal of Gastroenterology
2005-06
期刊論文
Potential diagnostic and prognostic values of detecting promoter hypermethylation in the serum of patients with gastric cancer.
Leung WK*, To KF, Chu ES, Chan MW, Bai AH, Ng EK, Chan FK, Sung JJ
British Journal of Cancer
2005-05
期刊論文
Promoter hypermethylation of Death-associated protein-kinase gene associated with advance stage gastric cancer.
Chan AW, Chan MW, Lee TL, Ng EK, Leung WK, Lau JY, Tong JH, Chan FK, To KF*
Oncology Reports
2005-04
期刊論文
Anti-sense trefoil factor family-3 (intestinal trefoil factor) inhibits cell growth and induces chemosensitivity to adriamycin in human gastric cancer cells.
Promoter hypermethylation of tumor-related genes in the progression of colorectal neoplasia.
Bai AH, Tong JH, To KF, Chan MW, Man EP, Lo KW, Lee JF, Sung JJ, Leung WK*
International Journal of Cancer
2004-11
期刊論文
Detection of epigenetic changes in fecal DNA as a molecular screening test for colorectal cancer: a feasibility study
Leung WK*, To KF, Man EP, Chan MW, Bai AH, Hui AJ, Chan FK, Lee JF, Sung JJ
Clinical Chemistry
2004-10
期刊論文
Constitutional activation of IL-6-mediated JAK/STAT pathway through hypermethylation of SOCS-1 in human gastric cancer cell line.
To KF*, Chan MW, Leung WK, Ng EK, Yu J, Bai AH, Lo AW, Chu SH, Tong JH, Lo KW, Sung JJ, Chan FK
British Journal of Cancer
2004-08
期刊論文
Quantitative detection of methylated SOCS-1 , a tumor suppressor gene, by a modified protocol of quantitative real time methylation-specific PCR using SYBR green and its use in early gastric cancer detection.
MChan MW, Chu ES, To KF, Leung WK*
Biotechnology Letters
2004-05
期刊論文
Effect of peroxisome proliferator activated receptor gamma ligands on growth and gene expression profiles of gastric cancer cells.
Leung WK*, Bai AH, Chan VY, Yu J, Chan MW, To KF, Wu JR, Chan KK, Fu YG, Chan FK, Sung JJ
Gut
2003-06
期刊論文
Hypermethylation of the tumor suppressor gene RASSFIA and frequent concomitant loss of heterozygosity at 3p21 in cervical cancers.
Yu MY, Tong JH, Chan PK, Lee TL, Chan MW, Chan AW, Lo KW, To KF*
International Journal of Cancer
2003-06
期刊論文
Inactivation of helicase-like transcription factor by promoter hypermethylation in human gastric cancer.
Leung WK*, Yu J, Bai AH, Chan MW, Chan KK, To KF, Chan FK, Ng EK, Chung SC, Sung JJ
Molecular Carcinogenesis
2003-05
期刊論文
Absence of cyclin D2 expression is associated with promoter hypermethylation in gastric cancer.
Yu J, Leung WK*, Ebert MP, Leong RW, Tse PC, Chan MW, Bai AH, To KF, Malfertheiner P, Sung JJ
British Journal of Cancer
2003-05
期刊論文
Frequent hypermethylation of promoter region of RASSF1A in tumor tissues and voided urine of urinary bladder cancer patients.
Chan MW, Chan LW, Tang NL, Lo KW, Tong JH, Chan AW, Cheung HY, Wong WS, Chan PS, Lai FM, To KF*
International Journal of Cancer
2002-12
期刊論文
Promoter hypermethylation of tumor-related genes in gastric intestinal metaplasia of patients with and without gastric cancer.
To KF, Leung WK*, Lee TL, Yu J, Tong JH, Chan MW, Ng EK, Chung SC, Sung JJ
International Journal of Cancer
2002-08
期刊論文
Expression of trefoil peptides (TFF1, TFF2, and TFF3) in gastric carcinomas, intestinal metaplasia, and non-neoplastic gastric tissues.
Leung WK*, Yu J, Chan FK, To KF, Chan MW, Ebert MP, Ng EK, Chung SC, Malfertheiner P, Sung JJ
Journal of Pathology
2002-08
期刊論文
Quantitative Epstein-Barr virus DNA analysis and detection of gene promoter hypermethylation in nasopharyngeal (NP) brushing samples from patients with NP carcinoma.
Tong JH, Tsang RK, Lo KW, Woo JK, Kwong J, Chan MW, Chang AR, van Hasselt CA, Huang DP, To KF*
Clinical Cancer Research
2002-06
期刊論文
Detection of gene promoter hypermethylation in the tumor and serum of patients with gastric carcinoma
Lee TL, Leung WK, Chan MW, Ng EK, Tong JH, Lo KW, Chung SC, Sung JJ, To KF*
Clinical Cancer Research
2002-02
期刊論文
Hypermethylation of multiple genes in tumor tissues and voided urine in urinary bladder cancer patients
Chan MW, Chan LW, Tang NL, Tong JH, Lo KW, Lee TL, Cheung HY, Wong WS, Chan PS, Lai FM, To KF*
Clinical Cancer Research
2001-12
期刊論文
Alterations of frizzled (FzE3) and Secreted Frizzled Related Protein (hsFRP) Expression in Gastric Cancer
To KF*, Chan MWY, Leung WK, Lee TL, Tong JHM, Sung JJY
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