High‐Throughput 96‐Well Nanogroove‐Enhanced Electrical Impedance Biosensor for Real‐Time Label‐Free Cancer Drug Screening
Jong Seob Choi, Hye‐Bin Park, Su Han Lee, Byunggik Kim, Jihoon Lee, Sang‐Keun Sung, Chia‐Yi Su, JuKyung Lee, Seongjun Jang, Yongjin Lee, Jung Hyun Lee, Hyung Jin Kim, Deok‐Ho Kim
Advanced Healthcare Materials
2023-12
期刊論文
NEDD8 promotes radioresistance via triggering autophagy formation and serves as a novel prognostic marker in oral squamous cell carcinoma
Tsu-Zong Yuan, Hui-Yu Lin, Chia-Hao Kuei, Che-Hsuan Lin, Hsun-Hua Lee, Hsin-Lun Lee, Hsiao-Wei Lu, Chia-Yi Su, Hui-Wen Chiu, Yuan-Feng Lin
Cancer Cell International
2023-04
期刊論文
Tumor stromal topography promotes chemoresistance in migrating breast cancer cell clusters
Chia-Yi Su, Alex Wu, Zhipeng Dong, Chris P. Miller, Allister Suarez, Andrew J. Ewald, Eun Hyun Ahn, Deok-Ho Kim
Biomaterials
2023-03
期刊論文
Matrix Anisotropy Promotes a Transition of Collective to Disseminated Cell Migration via a Collective Vortex Motion
Chia‐Yi Su, Tatsuya Matsubara, Alex Wu, Eun Hyun Ahn, Deok‐Ho Kim
Advanced Biology
2022-11
期刊論文
Changes of mutations and copy-number and enhanced cell migration during breast tumorigenesis
Seung Hyuk T. Lee, Joon Yup Kim, Peter Kim, Zhipeng Dong, Chia-Yi Su, Eun Hyun Ahn
Advanced Biology
2022-09
期刊論文
AIM2 upregulation promotes the metastatic progression and PD-L1 expression in lung adenocarcinoma
Jing-Quan Zheng, Che-Hsuan Lin, Hsun-Hua Lee, Wei-Ming Chang, Li-Jie Li, Chia-Yi Su, Kang-Yun Lee, Hui-Wen Chiu, Yuan-Feng Lin
Cancer Science
2022-08
期刊論文
The aberrant cancer metabolic gene carbohydrate sulfotransferase 11 promotes non-small cell lung cancer cell metastasis via dysregulation of ceruloplasmin and intracellular iron balance
FAS receptor regulates NOTCH activity through ERK-JAG1 axis activation and controls oral cancer stemness ability and pulmonary metastasis
Li-Jie Li, Peter Mu-Hsin Chang, Chien-Hsiu Li, Yu-Chan Chang, Tsung-Ching Lai, Chia-Yi Su, Chi-Long Chen, Wei-Min Chang, Michael Hsiao, Sheng-Wei Feng
Cell Death Discovery
2021-08
期刊論文
Engineering a 3D collective cancer invasion model with control over collagen fiber alignment
Chia-Yi Su, Alice Burchett, Matthew Dunworth, Jong Seob Choi, Andrew J Ewald, Eun Hyun Ahn, Deok-Ho Kim
Biomaterials
2020-04
期刊論文
Monoamine Oxidase B Expression Correlates with a Poor Prognosis in Colorectal Cancer Patients and Is Significantly Associated with Epithelial-to-Mesenchymal Transition-Related Gene Signatures
Yi-Chieh Yang, Ming-Hsien Chien, Tsung-Ching Lai, Chia-Yi Su, Yi-Hua Jan, Michael Hsiao, Chi-Long Chen
International Journal of Molecular Sciences
2019-09
期刊論文
Therapeutic Targeting of Aldolase A Interactions Inhibits Lung Cancer Metastasis and Prolongs Survival
Yu-Chan Chang, Jean Chiou, Yi-Fang Yang, Chia-Yi Su, Yuan-Feng Lin, Chia-Ning Yang, Pei-Jung Lu, Ming-Shyan Huang, Chih-Jen Yang, Michael Hsiao
Cancer Research
2019-05
期刊論文
Microphysiological Systems as Enabling Tools for Modeling Complexity in the Tumor Microenvironment and Accelerating Cancer Drug Development
Hong Nam Kim, Nicole L. Habbit, Chia-Yi Su, Nakwon Choi, Eun Hyun Ahn, Elizabeth A. Lipke, Deok-Ho Kim
Advanced Functional Materials
2018-09
期刊論文
Biomechanical interplay between anisotropic re-organization of cells and the surrounding matrix underlies transition to invasive cancer spread
Deok-Ho Kim, Andrew J Ewald, JinSeok Park, Kshitiz, Moonkyu Kwak, Ryan S Gray, Chia-Yi Su, Jayhyun Seo, Steven S An, Andre Levchenko
Scientific Reports
2017-09
期刊論文
Feedback regulation of ALDOA activates the HIF-1α/MMP9 axis to promote lung cancer progression
Yu-Chan Chang, Yung-Chieh Chan, Wei-Ming Chang, Yuan-Feng Lin, Chih-Jen Yang, Chia-Yi Su, Ming-Shyan Huang, Alexander T H Wu, Michael Hsiao
Cancer Letters
2017-08
期刊論文
Decrease of FSTL1-BMP4-Smad signaling predicts poor prognosis in lung adenocarcinoma but not in squamous cell carcinoma
Jean Chiou, Chia-Yi Su, Yi-Hua Jan, Chih-Jen Yang, Ming-Shyan Huang, Yung-Luen Yu, Michael Hsiao
Scientific Reports
2017-08
期刊論文
Secretory RAB GTPase 3C modulates IL6-STAT3 pathway to promote colon cancer metastasis and is associated with poor prognosis
Yu-Chan Chang, Chia-Yi Su (co-first), Ming-Huang Chen, Wei-Shone Chen, Chi-Long Chen, Michael Hsiao
Molecular Cancer
2017-01
期刊論文
Glucose transporter 4 promotes head and neck squamous cell carcinoma metastasis through the TRIM24-DDX58 axis
Yu-Chan Chang, Li-Hsing Chi, Wei-Ming Chang, Chia-Yi Su, Yuang-Feng Lin, Chi-Long Chen, Ming-Huang Chen, Peter Mu-Hsin Chang, Alex T. H. Wu, Michael Hsiao
Journal of Hematology & Oncology
2017-01
期刊論文
Parathyroid Hormone-Like Hormone is a Poor Prognosis Marker of Head and Neck Cancer and Promotes Cell Growth via RUNX2 Regulation
Inhibition of VEGF165/VEGFR2-dependent signaling by LECT2 suppresses hepatocellular carcinoma angiogenesis
Chi-Kuan Chen, Wen-Hsuan Yu, Tsu-Yao Cheng, Min-Wei Chen, Chia-Yi Su, Yi-Chieh Yang, Tsang-Chih Kuo, Ming-Tsan Lin, Ya-Chi Huang, Michael Hsiao, Kuo-Tai Hua, Mien-Chie Hung, Min-Liang Kuo
Scientific Reports
2016-08
期刊論文
The opposite prognostic effect of NDUFS1 and NDUFS8 forms a prognostic panel for non-small cell lung cancer by reflecting the oncojanus role of mitochondrial complex I
Chia-Yi Su, Yu-Chan Chang, Chih-Jen Yang, Ming-Shyan Huang, Michael Hsiao
Scientific Reports
2016-06
期刊論文
Cytosolic PKM2 stabilizes mutant EGFR protein expression through regulating HSP90-EGFR association
Y-C Yang, T-Y Cheng, S-M Huang, C-Y Su, P-W Yang, J-M Lee, C-K Chen, M Hsiao, K-T Hua, M-L Kuo
Oncogene
2016-05
期刊論文
Therapeutic targeting of methylthioadenosine phosphorylase
Yu-Chan Chang, Chia-Yi Su, Michael Hsiao
Cancer Cell & Microenvironment
2016-04
期刊論文
Huntingtin-Interacting Protein-1 Is an Early-Stage Prognostic Biomarker of Lung Adenocarcinoma and Suppresses Metastasis via Akt-mediated Epithelial-Mesenchymal Transition
Che-Yu Hsu, Cheng-Han Lin, Yi-Hua Jan, Chia-Yi Su, Yun-Chin Yao, Hui-Chuan Cheng, Tai-I Hsu, Po-Shun Wang, Wen-Pin Su, Chih-Jen Yang, Ming-Shyan Huang, Marcus J Calkins, Michael Hsiao, Pei-Jung Lu
American Journal of Respiratory and Critical Care Medicine
2016-03
期刊論文
The nucleolar protein NIFK promotes cancer progression via CK1α/β-catenin in metastasis and Ki-67-dependent cell proliferation
Ghrelin promotes renal cell carcinoma metastasis via Snail activation and is associated with poor prognosis
Tsung-Chieh Lin, Yu-Peng Liu, Yung-Chieh Chan, Chia-Yi Su, Yuan-Feng Lin, Shih-Lan Hsu, Chung-Shi Yang, Michael Hsiao
Journal of Patholology
2015-07
期刊論文
DDX3 as A Strongest Prognosis Marker and Its Downregulation Promotes Metastasis in Colorectal Cancer
Chia-Yi Su, Tsung-Chieh Lin, Yuan-Feng Lin, Ming-Huang Chen, Chien-Hsin Lee, Hsuan-Yao Wang, Yu-Chieh Lee, Yu-Peng Liu, Chi-Long Chen, Michael Hsiao
Oncotarget
2015-07
期刊論文
Plasminogen Activator Inhibitor- 2 Plays a Leading Prognostic Role among Protease Families in Non-Small Cell Lung Cancer
Chia-Yi Su, Yu-Peng Liu, Chih-Jen Yang, Yuan-Feng Lin, Jean Chiou, Li-Hsing Chi, Jih-Jong Lee, Alex T H Wu, Pei-Jung Lu, Ming-Shyan Huang, Michael Hsiao
PLoS One
2014-09
期刊論文
MTAP is an independent prognosis marker and the concordant loss of MTAP and p16 expression predicts short survival in non-small cell lung cancer patients
Chia-Yi Su, Yu-Chan Chang, Yung-Chieh Chan, Tsung-Chieh Lin, Ming-Shyan Huang, Chih-Jen Yang, Michael Hsiao
European Journal of Surgical Oncology
2014-09
期刊論文
Squalene synthase induces tumor necrosis factor receptor 1 enrichment in lipid rafts to promote lung cancer metastasis
Yi-Fang Yang, Yi-Hua Jan, Yu-Peng Liu, Chih-Jen Yang, Chia-Yi Su, Yu-Chan Chang, Tsung-Ching Lai, Jean Chiou, Hong-Yuan Tsai, Jean Lu, Chia-Ning Shen, Jin-Yuh Shew, Pei-Jung Lu, Yuan-Feng Lin, Ming-Shyan Huang, Michael Hsiao
American Journal of Respiratory and Critical Care Medicine
2014-07
期刊論文
Inhibition of G9a induces DUSP4-dependent autophagic cell death in head and neck squamous cell carcinoma
Kai-Chun Li, Kuo-Tai Hua, Yi-Shen Lin, Chia-Yi Su, Jenq-Yuh Ko, Michael Hsiao, Min-Liang Kuo, Ching-Ting Tan
Molecular Cancer
2014-04
期刊論文
MicroRNA-18a is elevated in prostate cancer and promotes tumorigenesis through suppressing STK4 in vitro and in vivo
T-I Hsu, C-H Hsu, K-H Lee, J-T Lin, C-S Chen, K-C Chang, C-Y Su, M Hsiao, P-J Lu
Oncogenesis
2012-07
期刊論文
Clinicopathological analysis of β-catenin and Axin-1 in solid pseudopapillary neoplasms of the pancreas
Chief educational attainment