研究人才詳細資料
主要學歷
| 出版年月 | 著作類別 | 著作名稱 | 作者 | 收錄出處 |
|---|---|---|---|---|
| 2020-11 | 期刊論文 | Rationally derived inhibitors of hepatitis C virus (HCV) p7 channel activity reveal prospect for bimodal antiviral therapy. | J. Shaw, R. Gosein, M. M. Kalita, T. L. Foster, J. Kankanala, D. R. Mahato, S. Abas, B. J. King, C. Scott, E. Brown, M. J. Bentham, L. Wetherill, A. Bloy, A. Samson, M. Harris, J. Mankouri, D. Rowlands, A. Macdonald, A. W. Tarr, W. B. Fischer, R. Foster, S. Griffin | Elife |
| 2020-02 | 期刊論文 | Membrane partitioning of peptide aggregates - coarse grained molecular dynamics simulations. | Y.-H. Lien, D. R. Mahato, F. Hoppe-Seyler, W. B. Fischer | Journal of Biomolecular Structure and Dynamics |
| 2018-04 | 期刊論文 | Interaction of antivirals with a heptameric bundle model of the p7 protein of hepatitis C virus. | S. Dahl, M. M. Kalita, W. B. Fischer | Chemical Biology & Drug Design |
| 2017-08 | 期刊論文 | Specification of binding modes between a transmembrane peptide mimic of ATP6V0C and polytopic E5 of human papillomavirus-16. | D. R. Mahato, W. B. Fischer | Journal 0f Biomolecular Structure and Dynamics |
| 2017-07 | 期刊論文 | Decoupled side chain - backbone dynamics for proton translocation - M2 of influenza A. | M. M. Kalita, W. B. Fischer | Journal of Molecular Modeling |
| 2017-01 | 期刊論文 | Lipid rafts associated stomatin enhances cell fusion. | J.-H. Lee, C.-F. Hsieh, H.-W. Liu, C.-Y. Chen, S.-C. Wu, T.-W. Chen, C.-S. Hsu, Y.-H. Liao, C.-Y. Yang, J.-F. Shyu, W. B. Fischer, C.-H. Lin | The FASEB Journal |
| 2016-12 | 期刊論文 | Weak selectivity predicted for modeled bundles of the viral channel forming protein E5 of human papillomavirus-16. | D. R. Mahato, W. B. Fischer | The Journal of Physical Chemistry B |
| 2016-10 | 期刊論文 | Small molecule ligand docking to genotype specific bundle structures of hepatitis C virus (HCV) p7 protein | N. Laasch, M. M. Kalita, S. Griffin, W. B. Fischer | Computational Biology and Chemistry |
| 2016-07 | 期刊論文 | Asymmetric dynamics of ion channel forming proteins - hepatitis C virus (HCV) p7 bundles. | M. M. Kalita, W. B. Fischer | Biochimica et Biophysica Acta |
| 2016-07 | 期刊論文 | Viral channel forming proteins – how to assemble and depolarize lipid membranes in silico | W. B. Fischer, M. M. Kalita, D. Heermann | Biochimica et Biophysica Acta |
| 2016-06 | 期刊論文 | Membrane protein assembly: two cytoplasmic phosphorylated serine sites of Vpu from HIV-1 affect oligomerization. | C.-P. Chen, M.-H. Lin, Y.-T. Chan, L.-C. Chen, C. Ma, W. B. Fischer | Scientific Reports |
| 2016-02 | 期刊論文 | Patch formation of a viral channel forming protein within a lipid membrane – Vpu of HIV-1. | M.-H. Lin, C.-P. Chen, W. B. Fischer | Molecular BioSystems |
| 2016-01 | 期刊論文 | Interaction of ions with the luminal side of the WT and mutant skeletal muscle ryanodine receptor. | R. Schilling, R. H. A. Fink, W. B. Fischer | Journal of Molecular Modeling |
| 2015-12 | 期刊論文 | Development and characterizations of the recombinant human VEGF-EGF dual-targeting fusion protein as a drug delivery system. | J. J. Lin, K. L. Lan, S. F. Chang, Y. F. Chen, W. C. Tsai, P. H. Chiang, M.-H. Lin, W. B. Fischer, Y. S. Shih, S. H. Yen, R. Liu, Y. G. Tsay, H. E. Wang, C. A. Chang | Bioconjugate Chemistry |
| 2015-08 | 期刊論文 | Estimating binding free energy of a putative growth factors EGF-VEGF complex - a computational bioanalytical study. | M.-H. Lin, C. A. Chang, W. B. Fischer | Journal of Biomolecular Structure and Dynamics |
| 2015-06 | 期刊論文 | Genotype-specific differences in structural features of hepatitis C virus (HCV) p7 membrane protein. | M. M. Kalita, S. Griffin, J. J. Chou, and W. B. Fischer | Biochimica et Biophysica Acta |
| 2015-02 | 期刊論文 | Structure based computational assessment of channel properties of assembled ORF-8a from SARS-CoV. | H.-J. Hsu, M.-H. Lin, C. Schindler, W. B. Fischer | Proteins |
| 2014-11 | 期刊論文 | Docking assay of small molecule antivirals to p7 of HCV | Leon Bichmann, Yi-Ting Wang, Wolfgang B. Fischer | Computational Biology and Chemistry |
| 2014-06 | 期刊論文 | Ion-dynamics in hepatitis C virus p7 helical transmembrane domains — a molecular dynamics simulation study | Yi-TingWang, Roman Schilling, Rainer H.A. Fink, Wolfgang B. Fischer | Biophysical Chemistry |
| 2014-04 | 期刊論文 | Correlation of biological activity with computationally derived structural features from transmembrane hetero-dimers of HIV-1 Vpu with host factors | Li-Hua Li, Wolfgang B. Fischer | Biochimica et Biophysica Acta |
| 2014-04 | 期刊論文 | MD simulations of the central pore of ryanodine receptors and sequence comparison with 2B protein from coxsackie virus | Roman Schilling , Rainer H.A. Fink , Wolfgang B. Fischer | Biochimica et Biophysica Acta |
| 2014-04 | 期刊論文 | Viral channel proteins in intracellular protein–protein communication:Vpu of HIV-1, E5 of HPV16 and p7 of HCV | Wolfgang B. Fischer, Li-Hua Li, Dhani Ram Mahato, Yi-TingWang, Chin-Pei Chen | Biochimica et Biophysica Acta |
| 2014-04 | 期刊論文 | Viral channel proteins in intracellular protein - protein communication: Vpu of HIV-1, E5 of HPV16 and p7 of HCV | W. B. Fischer, L.-H. Li, D. R. Mahato, Y.-T. Wang, C.-P. Chen | Biochimica et Biophysica Acta |
| 2013-10 | 期刊論文 | Membrane undulation induced by NS4A of Dengue virus: a molecular dynamics simulation study. | Meng-Han Lin, Hao-Jen Hsua, Ralf Bartenschlagerc and Wolfgang B. Fischer | Journal of Biomolecular Structure and Dynamics |
| 2013-09 | 期刊論文 | Computational modeling of the p7 monomer from HCV and its interaction with small molecule drugs. | Yi-Ting Wang, Hao-Jen Hsu and Wolfgang B Fischer | Springer Plus |
| 2013-03 | 期刊論文 | Assembling an Ion Channel: ORF 3a from SARS-CoV. | Tze-Hsiang Chien, Ya-Ling Chiang, Chin-Pei Chen, Petra Henklein, Karen Haeanel,Ing-Shouh Hwang, Dieter Willbold, Wolfgang B. Fischer | Biopolymers |
| 2013-01 | 期刊論文 | Assembling Viral Channel Forming Proteins: Vpu from HIV-1 | Li-Hua Li, Hao-Jen Hsu, Wolfgang B. Fischer | Biopolymers |
| 2012-07 | 期刊論文 | Sequence Alignment of Viral Channel Proteins with Cellular Ion Channels | CHRISTINA SCHINDLER* and WOLFGANG B. FISCHER |
電腦生物期刊 JOURNAL OF COMPUTATIONAL BIOLOGY |
| 2011-11 | 期刊論文 | Molecular dynamics simulations and conductance studies of the interaction of VP1 from Polio virus and gp41 fusion peptide from HIV-1 with lipid membranes. | GUO-SHENG HONG1, CHIN-PEI CHEN1, MENG-HAN LIN1, JENS KRÜGER1*, CHRISTIAN F. W. BECKER2, RAINER H. A. FINK3, & WOLFGANG B. FISCHER1 | Molecular Membrane Biology |
| 2011-10 | 專書論文 | Mechanism of Function of Viral Channel Proteins and Implications for Drug Development | Wolfgang B. Fischer,* Yi-Ting Wang,* Christina Schindler,*,1 and Chin-Pei Chen* | |
| 2011-05 | 期刊論文 | In silico investigations of possible routes of assembly of ORF 3a from SARS-CoV | Hao-Jen Hsu &Wolfgang B. Fischer | J Molecular Modeling |
| 2011-02 | 期刊論文 | Ultrasensitive in situ label-free DNA detection using a GaN nanowire-based extended-gate field-effect-transistor sensor. | C.-P. Chen, A. Ganguly, C.-Y. Lu, T.-Y. Chen, C.-C. Kuo, R.-S. Chen, W.-H. Tu, W. B. Fischer, L.-C. Chen* | Analytical Chemistry |
| 2010-12 | 期刊論文 | BST-2 is rapidly down-regulated from the cell surface by the HIV-1 protein Vpu: evidence for a post-ER mechanism of Vpu-action. | M. Skasko, A. Tokarev, C.-C. Chen, W. B. Fischer, S. K. Pillai, J. Guatelli* | Virology |
| 2010-11 | 期刊論文 | Ligand-protein docking studies of potential HIV-1 drug compounds using the algorithm FlexX. | . Patargias, G. Ewart, C. Luscombe, W. B. Fischer* | Anal. Bioanal. Chem. |
| 2010-08 | 期刊論文 | ORF 8a of the human severe acute respiratory syndrom coronavirus forms an ion channel: experiments and molecular dynamics simulations. | C.-C. Chen, J. Krüger, I. Sramala, P. Henklein, P. Henklein, Y.-M. A. Chen, W. B. Fischer* | Biochimica Biophysica Acta |
| 2010-05 | 期刊論文 | Viral channel forming proteins – modeling the target. | W. B. Fischer*, H.-J. Hsu | Biochimica Biophysica Acta |
| 2009-11 | 期刊論文 | Reconstructing Potentials of Mean Force from Short Steered Molecular Dynamics Simulations of Vpu from HIV-1 | G. Patargias , H. Martay , W. B. Fischer* | Journal of Biomolecular Structure & Dynamics |
| 2009-10 | 期刊論文 | Model generation of viral channel forming 2B protein bundles from polio and coxsackie viruses | G. Patargias, T. Barke, S. Cooper, A. Watts, W. B. Fischer* | Molecular Membrane Biology |
| 2009-09 | 期刊論文 | Assembly of Viral Membrane Proteins | J. Krüger, W. B. Fischer* | J. Chemical Theory and Computation |
| 2009-05 | 專書論文 | Viral Channel-Forming Proteins | W. B. Fischer*, J. Krüger | |
| 2009-01 | 期刊論文 | Lipid-induced conformation of helix 7 from the pore-forming domain of the Bacillus | K. Tiewsiri, W. B. Fischer, C. Angsuthanasombat* | Archives of Biochemistry and Biophysics |
| 2008-02 | 期刊論文 | Exploring the conformational space of Vpu from HIV-1: a versatile adaptable protein. | J. Krüger, W. B. Fischer* | Journal of Computational Chemistry |
| 2008-01 | 期刊論文 | Biophysical characterisation of Vpu from HIV-1 suggests a channel-pore dualism. | T. Mehnert, A. Routh, P. J. Judge, Y. H. Lam, D. Fischer, A. Watts, W. B. Fischer* | Proteins |
| 2007-06 | 期刊論文 | Towards a mechanism of function of the viral ion channel Vpu from HIV-1. | T. Mehnert, Y. H. Lam, P. Judge, A. Routh, D. Fischer, A. Watts, W. B. Fischer* | Journal of Biomolecular Structure and Dynamics |
| 2006-09 | 期刊論文 | Drug-protein interaction with Vpu from HIV-1: proposing binding sites for amiloride and one of its derivatives. | C. G. Kim, V. Lemaitre, A. Watts, W. B. Fischer* | Analytical and Bioanalytical Chemistry |
| 2006--- | 期刊論文 | Protein-protein interactions: modelling the Hepatitis C virus ion channel p7. | G. Patargias, N. Zitzmann, R. Dwek, W. B. Fischer* | Journal of Medicinal Chemistry |
| 2005--- | 期刊論文 | Computational analysis of mutations in the transmembrane region of Vpu from HIV-1. | A. Candler, M. Featherstone, R. Ali, L. Maloney, A. Watts, W. B. Fischer* | Biochimica Biophysica Acta |
| 2004--- | 期刊論文 | Interaction of amiloride and one of its derivatives with Vpu from HIV-1: a molecular dynamics simulation. | V. Lemaitre, R. Ali, C. G. Kim, A. Watts, W. B. Fischer* | FEBS Letters |
| 2003--- | 期刊論文 | The hepatitis C virus p7 protein forms an ion channel which is inhibited by long alkylchain iminosugar derivatives. | D. Pavlović, D. C. A. Neville, O. Argaud, B. Blumberg, R. A. Dwek, W. B. Fischer, N. Zitzmann* | Proceeding of the National Academy of Science USA |
| 2002--- | 期刊論文 | Bundles consisting of extended transmembrane segments of Vpu from HIV-1: computer simulations and conductance measurements. | F. Cordes, A. D. Tustian, M. S. P. Sansom, A. Watts, W. B. Fischer* | Biochemistry |