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研究人才詳細資料

出版年月	著作類別	著作名稱	作者	收錄出處
2022-09	期刊論文	Low-resolution description of the conformational space for intrinsically disordered proteins	Daniel Förster, Jérôme Idier, Leo Liberti, Antonio Mucherino, Jung-Hsin Lin and Thérèse E. Malliavin	Scientific Reports
2022-07	期刊論文	A curvilinear-path umbrella sampling approach to characterizing the interactions between rapamycin and three FKBP12 variants	Dhananjay C. Joshi, Charlie Gosse, Shu-Yu Huang and Jung-Hsin Lin	Frontiers in Molecular Biosciences
2022-01	期刊論文	Molecular dynamics simulations and Gaussian network model for designing antibody mimicking protein towards dengue envelope protein	Wei Lim Chonga, Visit Vao-soongnern, Piyarat Nimmanpipug, Chatchai Tayapiwatana, Jung-Hsin Lin, Yi-Ling Lin, Hui Yee Cheeg, Sharifuddin Md Zain, Noorsaadah Abd Rahman, Vannajan Sanghiran Lee	Journal of Molecular Liquids
2020-08	期刊論文	MD-JEEP: a New Release for Discretizable Distance Geometry Problems with Interval Data.	Antonio Mucherino, Douglas S. Gonçalves, Leo Liberti, Jung-Hsin Lin, Carlie Lavor, Nelson Maculan	Annals of Computer Sciences and Information Systems
2020-03	期刊論文	Quantitative phosphoproteomic analysis identifies the potential therapeutic target EphA2 for overcoming sorafenib resistance in hepatocellular carcinoma cells	Chih-Ta Chen, Li-Zhu Liao, Ching-Hui Lu, Yung-Hsuan Huang, Yu-Kie Lin, Jung-Hsin Lin & Lu-Ping Chow	Experimental & Molecular Medicine
2019-09	期刊論文	An Efficient Exhaustive Search for the Discretizable Distance Geometry Problem with Interval Data.	Antonio Mucherino and Jung-Hsin Lin	Annals of Computer Sciences and Information Systems
2019-04	期刊論文	Delineating protein-protein curvilinear dissociation pathways and energetics with naïve multiple-walker umbrella sampling simulations	Dhananjay C. Joshi and Jung-Hsin Lin	Journal of Computational Chemistry
2019-02	期刊論文	A Coarse-Grained Representation for Discretizable Distance Geometry with Interval Data	Antonio Mucherino, Jung-Hsin Lin, Douglas S. Gonçalves.	Lecture Notes in Computer Science
2018-10	期刊論文	Effect of Statin Use on the Risk of Medically Attended Acute Respiratory Illness among Influenza Vaccinated Elderly.	Hsien-Tsung Chiu, Li-Jiuan Shen, Yee-Chun Chen, Jung-Hsin Lin, Chi-Chuan Wang	Vaccine
2018-08	期刊論文	Structural insights into the gating of DNA passage by the topoisomerase II DNA gate	Shin-Fu Chen, Nan-Lan Huang, Jung-Hsin Lin, Chyuan-Chuan Wu, Ying-Ren Wang, Yu-Jen Yu, Michael K. Gilson, and Nei-Li Chan	Nature Communications
2017-06	期刊論文	Can ligands of different functional types induce distinct dynamics in G protein-coupled receptors?	Yu-Hsuan Chen and Jung-Hsin Lin*	Curr. Top. Med. Chem
2016-09	研討會論文	A new approach to the discretization of multidimensional scaling	Warley Gramacho, Antonio Mucherino, Jung-Hsin Lin, and Carlile Lavor
2016-01	期刊論文	Structure- and dynamics-based computational design of anticancer drugs	Jung-Hsin Lin*	Biopolymers
2015-07	期刊論文	Concurrent direct human leukocyte antigen (HLA) genotyping and genome-wide association study (GWAS) reveal major genetic determinants of anti-thyroid drug-induced agranulocytosis	Pei-Lung Chen, Shyang-Rong Shih, Pei-Wen Wang, Ying-Chao Lin, Chen-Chung Chu, Jung-Hsin Lin, Szu-Chi Chen, Ching-Chung Chang, Tien-Shang Huang, Keh Sung Tsai, Fen-Yu Tseng, Chih-Yuan Wang, Jin-Ying Lu, Wei-Yih Chiu, Chien-Ching Chang, Yu-Hsuan Chen, Yuan-Tsong Chen, Cathy Shen-Jang Fann, Wei-Shiung Yang and Tien-Chun Chang	Nature Communications
2015-07	期刊論文	Recovery of the poisoned topoisomerase II for DNA religation: coordinated motion of the cleavage core revealed with the microsecond atomistic simulation	Nanlan Huang and Jung-Hsin Lin*	Nucleic Acids Research
2015-05	期刊論文	Discovery of small molecules for fluorescent detection of complement activation product C3d	3. Ronald D Gorham, Vicente Nunez, Jung-Hsin Lin, Suzan HM Rooijakkers, Valentine I. Vullev, and Dimitrios Morikis	Journal of Medicinal Chemistry
2015-04	期刊論文	A newly designed molecule J2326 for Alzheimer's disease disaggregates amyloid fibrils and induces neurite outgrowth	Pei-Teh Chang, Rahul Subhash Talekar, Fan-Lu Kung, Ting-Rong Chern, Chen-Wei Huang, Qing-qing Ye, Min-Yan Yang, Chao-Wu Yu, Shin-Yu Lai, Ravindra Ramesh Deore, Jung-Hsin Lin, Chien-Shu Chen, Grace Shiahuy Chen, Ji-Wang Chern	Neuropharmacology
2015-04	期刊論文	Prediction of functional types of ligands for G protein-coupled receptors with dynamically discriminable states embedded in low dimension	Yu-Hsuan Chen, Jung-Hsin Lin	Lecture Notes in Computer Science
2015-03	期刊論文	Tetrahydropyran and tetrahydrofuran-containing diarylheptanoids from Hedychium coronarium Rhizomes.	Yi-Shan Lin, Jung-Hsin Lin, Chia-Chuan Chang, and Shoei-Sheng Lee	Journal of Natural Product
2015-02	專書論文	Scoring Functions for Fragment-Based Drug Discovery	Jui-Chih Wang and Jung-Hsin Lin	Fragment-Based Methods in Drug Discovery, Methods in Molecular Biology
2014-12	期刊論文	Cobalt(III)porphyrin to target G-quadruplex DNA	Laurent Sabater, Pei-Ju Fang, Chi-Fon Chang, Aurore De Rache, Enora Prado, Jerôme Dejeu, Antonio Garofalo, Jung-Hsin Lin, Jean-Louis Mergny, Eric Defrancq and Geneviève Pratviel	Dalton Transaction
2014-12	專書論文	Prediction of Binding Poses and Binding Affinities for Glycans and their Binding Proteins using a Robust Scoring Function for General Protein-Ligand Interactions	Nanlan Huang and Jung-Hsin Lin	Proceedings of the Beilstein Glyco-Bioinformatics Symposium 2013 -- Discovering the Subtleties of Sugars
2014-06	期刊論文	Drug-Induced Conformational Population Shifts in Topoisomerase-DNA Ternary Complexes	Nanlan Huang and Jung-Hsin Lin	Molecules
2014-04	期刊論文	AID downregulation is a novel function of the DNMT inhibitor 5-aza-deoxycytidine	Chiou-Tsun Tsai, Pei-Ming Yang, Ting-Rong Chern, Shu-Hui Chuang, Jung-Hsin Lin, Lars Klemm, Markus Müschen and Ching-Chow Chen	Oncotarget
2013-05	期刊論文	Design and synthesis of dual-action inhibitors targeting histone deacetylases and HMG-CoA reductase for cancer treatment	Jhih-Bin Chen , Ting-Rong Chern , Tzu-Tang Wei , Ching-Chow Chen , Jung-Hsin Lin*, and Jim-Min Fang	J. Med. Chem.
2013-03	期刊論文	Scoring functions for prediction of protein-ligand interactions	Jui-Chih Wang and Jung-Hsin Lin	Curr. Pharm. Des.
2012-12	期刊論文	Target prediction of small molecules with information of key molecular interactions	Jung-Hsin Lin	Curr. Top. Med. Chem.
2012-08	期刊論文	AutoBind: Automatic extraction of protein-ligand binding affinity data from biological literature	Darby Tien-Hao Chang, Chao-Hsuan Ke, Jung-Hsin Lin, and Jung-Hsien Chiang	Bioinformatics
2012-08	期刊論文	When cytokinin, a plant hormone, meets the adenosine A2A receptor: A new neuroprotectant and lead for treating neurodegenerative disorders?	Yi-Chao Lee, Ying-Chen Yang, Chuan-Lin Huang, Tsun-Yung Kuo, Jung-Hsin Lin, De-Ming Yang, Nai-Kuei Huang	PLoS ONE
2012-08	期刊論文	idTarget: a web server for identifying proteins targets of small chemical molecules with robust scoring functions and a divide-and-conquer docking approach	Jui-Chih Wang, Pei-Ying Chu, Chung-Ming Chen and Jung-Hsin Lin	Nucleic Acids Research
2012-02	期刊論文	Discovery of N-Arylalkyl-3-hydroxy-4-oxo-3,4-dihydroquinazolin-2- carboxamide derivatives as HCV NS5B polymerase inhibitors	Ravindra Ramesh Deore, Grace Shiahuy Chen, Pei-Teh Chang, Ting-Rong Chern, Shin-Yu Lai, Ming-Hsieh Chuang, Jung-Hsin Lin, Fan-Lu Kung, Chien-Shu Chen, Chun-Tang Chiou, Ji-Wang Chern	ChemMedChem
2011-10	期刊論文	Robust scoring functions for protein-ligand interactions with quantum chemical charge models	Jui-Chih Wang,Jung-Hsin Lin,*Chung-Ming Chen, Alex L. Perryman, Arthur J. Olson	J. Chem. Inf. Model.
2011-09	期刊論文	A new drug design targeting the adenosinergic system for Huntington's disease	N.-K. Huang,¥ Jung-Hsin Lin,¥ J.-T. Lin, C.-I. Lin, E. M. Liu, C.-J. Lin, ..., J.-M. Fang,* Y.-L. Lin,* Y. Chern*	PLoS ONE
2011-09	期刊論文	Improvement of porphyrins for G-quadruplex DNA targeting	C. Romera, O. Bombarde, R. Bonnet, D. Gomez, P. Dumy, P. Calsou, J.-F. Gwan, Jung-Hsin Lin, E. Defrancq, G. Pratviel	Biochimie
2011-08	期刊論文	Binding change mechanism of membrane-bound Fo rotary motor driven by proton motive force	Jung-Hsin Lin	European Biophysics Journal with Biophysics Letters
2011-08	期刊論文	Design and Synthesis of Novel Dual-Action Compounds Targeting Adenosine A<sub>2A</sub> Receptor and Adenosine Transporter for Neuroprotection	J.-B. Chen, E. M. Liu, T.-R. Chern, C.-W. Yang, C.-I. Lin, N.-K. Huang, Y.-L. Lin, Y. Chern,Jung-Hsin Lin,, Jim-Min Fang	ChemMedChem
2011-01	期刊論文	Accommodating protein flexibility for structure-based drug design	Jung-Hsin Lin*	Current Topics in Medicinal Chemistry
2010-12	期刊論文	Robust regression analysis of protein-ligand binding free energy models: toward identification of druggable genomes	Jui-Chih Wang and Jung-Hsin Lin*	International Journal of Systems and Synthetic Biology
2010-06	期刊論文	On the design of optimization algorithms for prediction of molecular interactions	Darby Tien-Hao Chang, Jung-Hsin Lin, Chih-Hung Hsieh, and Yen-Jeng Oyang*	Int. J. Art. Intell. Tools
2010-05	期刊論文	Improved enamine-type addition of dehydroaporphine using microwave irradiation	Wei-Jan Huang, Chih-Chiang Huang, Ling-Wei Hsin, Yeun-Min Tsai, Chin-Ting Lin, Jung-Hsin Lin, and Shoei-Sheng Lee	Tetrahedron Letters
2010-03	期刊論文	Molecular dynamics simulations of the rotary motor F0 under external electric fields across the membrane	Yang-Shan Lin, Jung-Hsin Lin*, Chien-Cheng Chang	Biophysical Journal
2010-02	期刊論文	Inhibition of histone deacetylase activity is a novel function of antifolate drug methotrexate	Pei-Ming Yang, Jung-Hsin Lin,, Wen-Yu Huang, Yi-Chu Lin, Shu-Hao Yeh, aChing-Chow Chen	Biochemical and Biophysical Research Communications
2010-02	專書論文	Structure and dynmics of large biological molecules: ATP-binding cassette (ABC) transporters	Jung-Hsin Lin, Jaakko Akola, and Robert O. Jones
2009-07	期刊論文	SLITHER: a web server for generating contiguous conformations of substrate molecules entering into deep active sites of proteins or migrating through channels in membrane transporters	林榮信	Nucleic Acids Research
2008-04	期刊論文	Statins increase p21 expression through inhibition of HDAC activity and release of promoter-associated HDAC1/2	Yi-Chu Lin, Jung-Hsin Lin, Chia-Wei Chou, Yu-Fan Chang, Shu-Hao Yeh, and Ching-Chow Chen	Cancer Research
2007-06	期刊論文	Remarkable Loop Flexibility in Avian Influenza N1 and its Implications for Antiviral Drug Design	1. R. E. Amaro, D. D. L. Minh, L. S. Cheng, W. M. Lindstrom, Jr., A. J. Olson, J.-H. Lin, W. W. Li a	Journal of the American Chemical Society
2007-01	期刊論文	Preparation of secolycorines against acetylcholinesterase	SS Lee, U Venkatesham, CP Rao, SH Lam, JH Lin	Bioorganic & Medicinal Chemistry
2006-07	期刊論文	Protemot: prediction of protein-binding sites with automatically extracted geometrical templates	林榮信	Nucleic Acids Research
2006-06	期刊論文	Restrained molecular dynamics simulations of HIV-1 protease: The first step in validating a new target for drug design	林榮信	Biopolymers
2006-05	期刊論文	Optimization and computational evaluation of a series of potential active site inhibitors of the V82F/I84V drug-resistant mutant of HIV-protease: An application of the relaxed complex method of structure-based drug design	林榮信	Chemical Biology & Drug Design
2006-01	期刊論文	A simple electrostatic switch important in the activation of type I protein kinase A by cyclic AMP	林榮信	Protein Science
2006-01	期刊論文	Increased Membrane Affinity of the C1 Domain of Protein Kinase C Compensates for the Lack of Involvement of its C2 Domain in Membrane Recruitment	林榮信	Journal of Biological Chemistry
2005-07	期刊論文	MEDock: a web server for efficient prediction of ligand binding sites based on a novel optimization algorithm	Tien-Hau Chang, Yen-Jen Oyang, Jung-Hsin Lin*	Nucleic Acids Research
2004-04	期刊論文	HIV-1 protease molecular dynamics of a wild-type and of the V82F/I84V mutant: Possible contribution to resistance and a potential new target site for drug	林榮信	Protein Science
2003-02	期刊論文	The Relaxed Complex Method: Accommodating Receptor Flexibility for Drug Design with an Improved Scoring Function	林榮信	Biopolymers
2002-09	期刊論文	Bridging Implicit and Explicit Solvent Approaches for Membrane Electrostatics	林榮信	Biophysical Journal
2002-05	期刊論文	Computational Drug Design Accommodating Receptor Flexibility: The Relaxed Complex Scheme	林榮信	Journal of the American Chemical Society
2000-12	期刊論文	Adsorption of Melittin to a Lipid Bilayer: A Molecular Dynamics Study	林榮信	Journal of Molecular Liquids
2000-12	期刊論文	Molecular dynamics simulations of hydrophobic and amphiphilic proteins interacting with a lipid bilayer	林榮信	Computational and Theoretical Polymer Science
2000-04	期刊論文	Stability of a Melittin Pore in a Lipid Bilayer: A Molecular Dynamics Study	林榮信	Biophysical Journal